Low frequency ofBRAFandCDKN2Amutations in endometrial cancer

I-29: Fertility Preservation in Early, Low Grade Endometrial Cancer

Background Endometrial cancer is the most common gynecologic malignancy in the United States, with over 40,000 cases diagnosed each year, typically in the postmenopausal women. 25% of cases affect premenopausal women. 14% of endometrial cancers are diagnosed in women younger than 45 years old. 5% of these tumors are diagnosed in women younger than 40 years old. In this talk the learning objecti...

Endometrial cancer

 کانسر آندومتر شایعترین بدخیمی دستگاه تناسلی زنان است، که تقریبا 7 درصد کانسرهای زنان را شامل می شود و چهارمین کانسر زنان بعد از کانسرهای (پستان، ریه و کلورکتال) در آمریکا است.

Low allele frequency of MLH1 D132H in American colorectal and endometrial cancer patients.

PURPOSE Hereditary nonpolyposis colon cancer is caused by mutations in DNA mismatch repair genes, predominantly MLH1 and MSH2. Classic MLH1 mutations cause an approximately 20-fold increase in colorectal cancer susceptibility. Recently, we identified a hypomorphic allele, MLH1 D132H , which impairs, but does not completely eliminate the function of MLH1 in tumor suppression. MLH1 D132H confers ...

Prevalence of endometrial cancer in young patients

Background: Cancer of the endometrium is the most common gynecologic malignancy in western and industrial countries, and is the second most common in developing countries, therefore it is of special importance. Adenocarcinoma of the endometrium is the most common type of uterine cancer. The prevalence of endometrial cancer in young women under the age of 40 in western country is very low and ab...

Ovarian Metastasis in Endometriod Type Endometrial Cancer